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This principle may applied the surgical treatment malignant conditions in general, except, course, in the cases in which surgery intended as a preliminary step before long an interval should allowed between radiation and operation. The early response tissues subjected radiation consists essentially in a modified inflammatory reaction, beginning as usual with edema the reaction more intense and more localized, if radium used, and less intense and more diffused if roentgen rays are used.

The tissue cells gradually recover if the dose has been light there inhibition their reproduction and development if the dose has been moderate the cells may completely professional college application essay writers destroyed if the dose has been lethal. The products such destruction are removed autolysis and absorption, and later are replaced fibrosis.

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This true normal as well as pathologic cells.

Generally neoplastic cells are more sensitive radiation editing thesis than normal tissue cells, and this fact based the entire radiation In many patients radiation produces so-called deep radiation sickness, a temporary state characterized nausea with or without vomiting which may quite pronounced, anorexia, headache, a sensation general weakness, nervousness, and sometimes fever.

This state may last in some degree for from a few hours several days a few patients remain nauseated and weak for as long as two weeks, how to write my paper during which time they eat little and lose weight.

Such reaction, which usually shorter and much less severe in persons treated with radium than in those treated with roentgen rays should allowed subside completely before the patient subjected the ordeal a major operation. As a rule, severe reactions are observed only when some part the abdomen has been treated, and this particularly true the upper half. Therefore, the interval between radiation and operation must depend largely the relative importance these factors in a given case.

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In carcinoma the breast radiation sickness usually either absent or slight and the operation could readily follow within a week.

In carcinoma the uterus, however, the radiation administered means radium internally and external roentgenization, and the interval should After radiation the tissues should in comparatively good condition for operation, and the surgeon should not encounter any particular delay in the repair the wound.

It doubtful if the surgeon will have any difficulties in carrying out the various steps the operation, after a single course treatment, especially if a proper interval has been allowed before operation. Even though the operation made more difficult radiation, few surgeons would hesitate adopt if the final results from t standpoint the patient can improved. Preoperative radiation should also tend minimize the danger tampering with a malignant lesion in order obtain a specimen for diagnosis. Postoperative radiation. Postoperative radiation may and often more or less illusory. The most important requirements in rendering innocuous such invisible malignant elements as may have remained after surgical ablation a correct selection the agent and its use in adequate dosage. Should radium or roentgen rays used? If wish sterilize an entire region, as following removal the breast, radiation should administered not only the field operation, but its lymphatic drainage. Roentgen rays properly applied will best meet the condition. Radium should reserved for small well-defined territories, especially if the agent can essay writing service recommendation introduced into the center or the substance the tissues, as the vaginal vault following hysterectomy in conjunction with roentgen ray from the outside, or into the cavity left after the removal a tumor limited size. However, in the latter, the radium should preferaly introduced at the time and as a part the operation. Radium used postoperatively, and blindly pushed or slipped into a drainage tube placed the surgeon at the time the operation IS, at best, a very uncertain procedure. dissertation proposal format If there has been no preoperative radiation, the patient should receive the treatment as soon as possible after operation. If the operation has been precedfd radiation the postoperative interval must governed the preoperative interval due consideration should allowed between operation and radiation.

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